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Rege, N.
- Polycystic Ovary Syndrome and Leucocytosis
Authors
1 MRC-KHS, Medical Research Centre-Kasturba Health Society, 17, K.D. Road,Vile Parle (West), Mumbai 400056, IN
2 Vasudha Clinic, Santacruz (west), Mumbai 400054, IN
3 Endocrine Metabolic Unit, MRC-KHS & Consultant, Vasudha Clinic, IN
Source
The Indian Practitioner, Vol 67, No 8 (2014), Pagination: 483-485Abstract
Polycystic ovary syndrome (PCOS) is a complex heterogeneous female reproductive endocrine disorder with multiple pathological mechanisms. Persistent leucocytosis, reflecting an underlying inflammation, is well recorded in obesity and diabetes; diseases with an underlying Insulin resistance (IR). Leucocytosis in PCOS has not been widely studied in spite of IR being considered as the important aetiopathological mechanism. The present communication explores the occurrence of leucocytosis in thirty patients of PCOS as compared to that in twenty six healthy regularly menstruating women.
- Prescription Monitoring of Hypertensive Patients Referred to Hypertension out Patient Department of a Tertiary Care Hospital, Mumbai
Authors
1 Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Parel, Mumbai, IN
2 Navi Mumbai Municipal Corporation, Seth GS Medical College and KEM Hospital, Parel, Mumbai, IN
3 Roche Products India Pvt Ltd, Mumbai, IN
Source
The Indian Practitioner, Vol 68, No 9 (2015), Pagination: 25-31Abstract
Introduction: The present study tried to establish the prescribing pattern, rationality of prescriptions and the awareness of patients about hypertension and the medicines given to them.Methods: This study of nine-month duration was conducted at the Hypertension Clinic in KEM hospital after obtaining permission from the IEC. The information was collected from new OPD patients of either sex with age between 18 and 80 years who were referred from intra hospital or from outside KEM hospital doctors for the first time, and who had received the prescription within last 6 months. Data collection was done using case record form (CRF) and a pre-validated questionnaire.
Results: Our study revealed that most of the patients were on monotherapy (53.92%). In the monotherapy category, the drugs used were calcium channel blockers (CCBs) 74.5%), beta-blockers (16.4%) and angiotensin converting enzyme (ACE) inhibitors (3.6%). Among those who were treated with drug combinations, 60.87% received two drugs, 26.09% received three drugs and 13.04% received four drugs. In combination therapy, beta-blocker and calcium channel blocker combination was given to the majority.
Ninety seven percent prescriptions were incomplete in various aspects of non drug therapy and drug therapy. The most frequently prescribed non drug therapy was salt restricted diet (68.42%). Awareness of the participants was poor with regards to their disease, its complications and its therapy.
Conclusion: The present study represents the current prescribing trend for anti-hypertensive agents and it highlights certain shortcomings in the existing prescribing practice.